The Effect of Variations in Blood pH
نویسندگان
چکیده
THE electrocardiographic response in man to acute changes in blood hydrogen ion concentration has not been well defined. Although the effects of an acute alteration in blood pH have been studied in dogs and isolated heart preparations, -4 examinations in man have usually been limited to clinical situations in which disturbances in serum electrolytes occurred along with deviations in hydrogen ion concentration.5 The present investigation is concerned with a study of the electrocardiogram in man during infusions of the acidifying and alkalinizing agents hydrochloric acid, the amine buffer tris (hydroxymethyl) aminomethane (THANM), and sodium bicarbonate.
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